Chondral injures present an unique exceptional challenge to the treating physician in view of the poor natural healing capacity of the articular cartilage cells
Articular cartilage is avascular and therefore has a limited repair capacity. The function of the articular cartilage is to allow lubricated low friction gliding movements of joints and to cushion the loading across the joint. Articular cartilage is made up of dense Type II collagen, a proteoglycan matrix and chondrocytes fixed within the matrix. The fluid contained as hydrostatic pressure within the homeostasis within the extracellular matrix of articular cartilage. This maintains the mechanical integrity of the articular cartilage to withstand the compressive loads across a joint and allow gliding and sliding movement..
Articular Cartilage Treatment Options
Non-Operative.
Operative
Arthroscopic Debridement (Chondroplasty):.
Marrow Stimulation (Microfracture): Osteochondral Transfer (Mosiacplasty) and OsteochondralAllografts:
Cell-Based Cartilage Repair Techniques
*Autologous Chondrocyte Implantation (ACT)/Matrix Autologous Chondrocyte Implantation (MACI):
ACI/MACI is suitable for athletes 20-50 years old with an isolated femoral condyle defect greater then 2-4 cm, less than 3-6mm deep.
Neocartilage Implantation
Neocartilage implantation involves sophisticated tissue engineering technology. The chondrocytes are harvested in a similar way to ACI, the cells are then expanded in a 2-D culture and seeded in a bovine collagen gel/sponge construct.